Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively
نویسندگان
چکیده
منابع مشابه
Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively.
CD100 represents the first semaphorin described in the immune system. It is expressed as a 300-kDa homodimer at the surface of most hematopoietic cells, but is also found in a soluble form following a proteolytic cleavage upon cell activation. We herein established that soluble CD100 (sCD100) impaired the migration of human monocytes and immature dendritic cells (DCs), but not of mature DCs. Pe...
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The Rnd family of proteins, Rnd1, Rnd2 and Rnd3, are atypical Rho family GTPases, which bind to but do not hydrolyse GTP. They interact with plexins, which are receptors for semaphorins, and are hypothesised to regulate plexin signalling. We recently showed that each Rnd protein has a distinct profile of interaction with three plexins, Plexin-B1, Plexin-B2 and Plexin-B3, in mammalian cells, alt...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2005
ISSN: 0953-8178,1460-2377
DOI: 10.1093/intimm/dxh224